Sickle Cell Information Center - Problem Oriented Clinical Guidelines

Edited by James Eckman, M.D. and Allan Platt, PA-C

Notice: These protocols are guideline in use at the Sickle Cell Center at Grady Health System, and they are intended for use by heath care providers treating patient with sickle cell syndromes. These guidelines are supplements to current text in general medicine, surgery and pediatrics. The recommendations for use and dosages of all medications is based on a review of current medical literature and 15 years of sickle cell acute care experience. The use of any drug should be preceded by a careful review of the package insert, which provides indications and dosages as approved by the United States Food and Drug Administration.

Introduction 

 Pathophysiology and Principles of Treatment  

 Health Maintenance 

  Emergency Room, Ambulance, and Triage Guidelines  

What do the Hemoglobin Electrophoresis Results mean?

Research Summary Article-2001

 

Specific Problems In Management

 Abdominal Pain  

Allergic Reaction

 Anemia - Aplastic and Hyperhemolytic Crisis

 Anesthesia an Preoperative Management 

 Aplastic Crisis  

 Back Pain  

 Bone Pain 

  Chelation Therapy and Iron Overload 

  Chest Pain and Chest Syndrome 

 Congestive Heart Failure 

Cough

 Depression  

Diarrhea

  Dysmenorrhea 

 Earaches and Hearing Loss  

 Edema 

 Eye Inflammation and Retinopathy  

Fever and Infections  

 Headaches 

 Hematuria and Nephropathy

 Hepatitis, Increased Jaundice 

 Hydroxyurea (Hydrea) Therapy 

  Hypertension  

 Leg Ulcers 

 Lymphadenopathy  

  Multi-organ System Failure  

Nasal Congestion and Bleeding  

Neurologic Symptoms and Stroke  

 Overdose 

 Pain Episodes  

 Pain Management 

 Pharyngitis and Sleep Apnea  

 Pregnancy  

 Priapism  

  Proteinuria and Renal Insufficiency  

 Sequestration Splenic and Hepatic

  Sickle Cell Trait  

 Substance Abuse and Addiction

 Transfusion Therapy 

 Urinary Track Symptoms and  Enuresis-

 Vaginitis