Nalbuphine HCL (Nubain - DuPont Pharmaceuticals)
Related to Naloxone and Oxymorphone
Potency similar to morphine
Onset in 2 - 3 minutes given I.V. slow push
Onset in 15 minutes given I.M.
Respiratory depression similar to morphine up to 0.15 mg/kg, then ceiling.
Analgesic ceiling at 0.30 mg/kg (20 mg for 70 kg patient)